You can do this by using an Expression.
SELECT max(number_one) * max(number_two) FROM exampleTable;
//SelfServicing
ResultsetFields fields = new ResultsetFields(1);
fields.DefineField(new EntityField("Total",
(OrderDetailsFields.UnitPrice.SetAggregateFunction(AggregateFunction.Max) * OrderDetailsFields.Quantity.SetAggregateFunction(AggregateFunction.Max))), 0);
DataTable results = new DataTable();
TypedListDAO dao = new TypedListDAO();
dao.GetMultiAsDataTable(fields, results, 0, null, null, null, true, null, null, 0, 0);
//Adapter
ResultsetFields fields = new ResultsetFields(1);
fields.DefineField(new EntityField2("Total",
(OrderDetailsFields.UnitPrice.SetAggregateFunction(AggregateFunction.Max) * OrderDetailsFields.Quantity.SetAggregateFunction(AggregateFunction.Max))), 0);
DataTable results = new DataTable();
DataAccessAdapter adapter = new DataAccessAdapter();
adapter.FetchTypedList(fields, results, null);