You need to remove a sortExpression from what? I mean, normally you use a SortExpression when fetching a collection and then you pass it to a collecton.GetMulti(....,sorter) call.
If you don't want to sort the collection simply don't pass your sort expression to it.
A SortExpression is a collection of SortClause objects. Maybe you want to remove a specific sort clause from the sorter. Here are some ways to do it:
var sorter = new SortExpression();
var sortClause = new SortClause(CustomerFields.City, SortOperator.Ascending);
sorter.Add(sortClause);
Assert.AreEqual(1, sorter.Count);
sorter.Remove(sortClause);
Assert.AreEqual(0, sorter.Count);
sorter.Add(sortClause);
Assert.AreEqual(1, sorter.Count);
sorter.Clear();
Assert.AreEqual(0, sorter.Count);
sorter.Add(sortClause);
sorter.RemoveAt(0);